This specific line refers back to the night of King Duncan's murder, specifically the moment when a knock at the door forced the couple to hurry to their chamber to avoid suspicion. Draft of the Full Speech Excerpt
This line highlights Lady Macbeth's transition from a cold, calculating figure to one "unhinged" by trauma and guilt. come_give_me_your_hand
To bed, to bed! there's knocking at the gate: come, come, come, come, give me your hand. What's done cannot be undone.—To bed, to bed, to bed! Analysis and Modern Usage This specific line refers back to the night
This dramatic moment is often used in acting classes and literature studies to show "character development through breakdown". come_give_me_your_hand