: Following his birth at the end of Season 4, Jamie becomes a central figure, leading to new dynamics like "baby gambling" among local fathers and Lois struggling to maintain her usual level of control.
: Directed by Bryan Cranston , this episode features Malcolm and Stevie needing the "unintelligent" Reese to help solve a complex scientific enzyme problem. Malcolm in The Middle - Season 5
: A two-part finale where Reese runs away to enlist after a heartbreak, and Hal faces potential jail time for his company’s legal troubles. Main Cast & Guest Stars Frankie Muniz Bryan Cranston Jane Kaczmarek Justin Berfield Erik Per Sullivan Christopher Masterson Notable Guest Cloris Leachman as Grandma Ida Notable Guest David Cassidy as Boone Vincent : Following his birth at the end of
: Hal faces several bizarre crises, including being falsely accused of insider trading and joining a group of fathers who bet on their babies' developmental milestones. Key Episodes & Moments Main Cast & Guest Stars Frankie Muniz Bryan
: The family travels to Las Vegas after Hal has a prophetic dream about a jackpot. Dewey and Reese enter an obese rabbit into a competition while Lois meets her favorite singer, Boone Vincent.