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In Jamaican patois, "Mampie" is a term of endearment for a full-figured or plus-sized woman. The track is a celebration of body positivity, with Shaggy dedicating the song to "all the girl-who-weight-lovers."
"Now this one dedicates to all the girl-who-weight-lovers... stay 'em inside and this I'm pleasing because I'm now Jamaican."