The game has gained a cult following on platforms like itch.io , where users praise its "ridiculous" premise, "exceptional dialogue," and unique set design. While some reviewers found the first game slightly stronger, the sequel is noted for having "way more poop" and entertaining cutscenes. Comments 94 to 55 of 148 - Poop Killer 2 by 616 GAMES

The game features different branching paths and endings depending on player actions, with a "continue" button available to make reaching alternate endings easier.

It is frequently described by players as a "whacky and wild" blend of gross-out comedy and indie horror .