(part 2) | [s4e16] House's Head
In the second part, "Wilson's Heart," the team discovers Amber is suffering from multisystem organ failure.
For more detailed production history and award information, you can visit the House's Head Wikipedia page and the Wilson's Heart Wikipedia page .
: Because amantadine binds to proteins, it cannot be cleared via dialysis. House must inform a devastated Wilson that there is no cure. Major Themes [S4E16] House's Head (Part 2)
: House is motivated by an unfamiliar sense of guilt. He ponders the unfairness of a "misanthropic drug addict" surviving while a promising young physician dies.
: The episode concludes with Thirteen testing positive for Huntington’s disease, echoing the theme that life is often "unfair" and beyond a doctor's control. In the second part, "Wilson's Heart," the team
The finale begins with House suffering from retrograde amnesia following a bus accident. Convinced he witnessed a life-threatening symptom in a fellow passenger before the crash, House undergoes increasingly dangerous procedures—including hypnosis and deep brain stimulation—to retrieve the lost memory.
: The recovered memory reveals that House, too drunk to drive, called Wilson for a ride; Amber arrived instead. They were on the bus together when the accident occurred. The Medical and Moral Failure House must inform a devastated Wilson that there is no cure
: House’s subconscious manifests a guide who prompts him to identify the patient. He eventually realizes her necklace is made of amber, signifying that the "dying patient" is actually Amber Volakis , Wilson’s girlfriend.
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